Windows 7 and Vista users may want to disable the Win+X shortcut keys in order to conserve screen space. To disable the shortcut keys, open the Control Panel and click on “Appearance and Personalization.” In the “Personalization” window, click on " Keyboard." In the “Keyboard” window, uncheck the box next to “Enable Win+X hotkeys.” ..
Turns out you can disable all the extra keys at once with a single registry entry, which I’ve provided as a downloadable registry hack.
Manual Registry Hack
Just open up regedit.exe through the start menu search box and navigate to the following key (create if it doesn’t exist)
Create a 32-bit DWORD value called NoWinKeys and set the value to 1. You’ll need to log on and back off for the changes to take effect.
Downloadable Registry Hack
To disable: Unzip the file and then double-click on the NoWinKeys.reg file to disable all the shortcut keys.
To enable: Unzip the file and then double-click on the RestoreWinKeys.reg file to re-enable all the shortcut keys.
Make sure that you log off and back on in order for this change to take effect. You could also restart explorer.exe through task manager if you wanted.
Download DisableWinKeys Registry Hack
